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US Patent 11222711 Predicting immunogenicity of T cell epitopes

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Is a

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Patent attributes

Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Ugur Sahin0

Arbel David Tadmor0

John Christopher Castle0

Martin Löwer0

Sebastian Boegel0

Date of Patent

January 11, 2022

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Patent Application Number

147871100

Date Filed

May 7, 2014

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Patent Citations Received

US Patent 12091443 Method of compact peptide vaccines using residue optimization

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US Patent 11464842 Compositions and method for optimized peptide vaccines using residue optimization

US Patent 11672850 Compositions and method for optimized peptide vaccines using residue optimization

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US Patent 11673936 Method of compact peptide vaccines using residue optimization

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US Patent 12064475 Compositions and method for optimized peptide vaccines using residue optimization

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US Patent 11464837 Immunogenic compositions comprising nucleic acids for RAS peptides

Patent Primary Examiner

Michael L Borin

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Patent abstract

The present invention relates to methods for predicting T cell epitopes. In particular, the present invention relates to methods for predicting whether modifications in peptides or polypeptides such as tumor-associated neoantigens are immunogenic or not. The methods of the invention are useful, in particular, for the provision of vaccines which are specific for a patient's tumor and, thus, in the context of personalized cancer vaccines.

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