Is a
Patent attributes
Patent Applicant
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Thoas Fioretos0
Karin Von Wachenfeldt0
Kjell Sjöström0
Marcus Järås0
Agneta Svedberg0
Cecilia Ann-Christin Malmborg Hager0
Helena Ågerstam0
Date of Patent
February 1, 2022
0Patent Application Number
169306310
Date Filed
July 16, 2020
0Patent Citations
Patent Primary Examiner
Patent abstract
The present invention provides an antibody or an antigen-binding fragment thereof with binding specificity for human interleukin-1 receptor accessory protein (IL1RAP) wherein the antibody or antigen-binding fragment is capable of inhibiting the binding of antibody ‘CAN04’ to human IL1RAP. The invention further provides the use of such antibodies or an antigen-binding fragments in the treatment and/or diagnosis of IL-1 associated diseases and conditions, including cancers such as acute myeloid leukemia and melanoma.
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