An apparatus for laser therapy comprises a frame on which a plurality of lasers slide at several wavelengths in motorized and automated manner for applying the laser on and through the skin and mucous membranes of a patient. The frame is also motorized, allowing installation on the patient without moving the patient from bed. The apparatus is programmed to determine treatment autonomously on the basis of parameters determined by the apparatus during pretreatment and to vary treatment parameters in real time for treatment optimization and safety purposes.