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US Patent 11274121 Methods for antibody drug conjugation, purification, and formulation

Patent 11274121 was granted and assigned to ImmunoGen on March, 2022 by the United States Patent and Trademark Office.

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Is a
Patent
Patent
0

Patent attributes

Patent Applicant
ImmunoGen
ImmunoGen
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Current Assignee
ImmunoGen
ImmunoGen
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
112741210
Patent Inventor Names
Daniel F. Milano0
Robert W. Herbst0
Richard A. Silva0
Michael R. Reardon0
Benjamin M. Hutchins0
Date of Patent
March 15, 2022
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Patent Application Number
162458900
Date Filed
January 11, 2019
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Patent Citations Received
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US Patent 11396543 Biparatopic FR-α antibodies and immunoconjugates
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US Patent 11834498 Biparatopic FR-alpha antibodies and immunoconjugates
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Patent Primary Examiner
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Sudhakar Katakam
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CPC Code
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A61K 31/5517
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A61K 31/5383
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C07K 16/2866
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A61K 47/6849
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G01N 33/6854
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C07K 1/16
0
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C07K 1/34
0
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C07K 16/00
0
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Methods of producing, purifying, and formulating antibody drug conjugates (ADCs) are provided herein. The methods use continuous conjugation processes, single-pass tangential flow filtration, countercurrent diafiltration, and/or in-line process automation technologies. The methods decrease process times and costs and improve product consistency.

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