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US Patent 11286293 Engineered immunoglobulin heavy chain-light chain pairs and uses thereof

Patent 11286293 was granted and assigned to Zymeworks Inc. on March, 2022 by the United States Patent and Trademark Office.

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The present invention provides heterodimer pairs that can comprise a first heterodimer and a second heterodimer wherein each heterodimer comprises an immunoglobulin heavy chain or fragment thereof and an immunoglobulin light chain or fragment thereof. At least one of the heterodimers can comprise one or more amino acid modifications in the C

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