The present invention relates to the technical field of bulbs, and discloses a waterproof bulb structure comprising a bulb shell, a lamp holder connected with the bulb shell, and further comprising a core column assembly and a rubber seal seat with an elastic waterproof seal; the core column assembly comprises a first conductive component, an LED light bar and a second conductive component that are electrically connected in sequence. The present invention has the following advantages: resistors are fixed at the rubber seal seat, with wires passing through sealing holes, and the first conductive component and the second conductive component are in fit with the sealing holes to prevent water or moisture from entering the bulb shell, so that water can be completely prevented from entering the bulb shell, and the lamp does not produce fogging when in use, and has good lighting effect and longer service life.