Is a
Patent attributes
Patent Applicant
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Michael Koepke0
Lars Nielsen0
Ryan Christopher Tappel0
Renato de Souza Pinto Lemgruber0
Esteban Marcellin0
James Bruce Yarnton Haycock Behrendorff0
Kaspar Valgepea0
Date of Patent
April 19, 2022
Patent Application Number
16152354
Date Filed
October 4, 2018
Patent Primary Examiner
The invention provides microorganisms and methods for the production of polyhydroxybutyrate (PHB) from gaseous substrates. In particular, the invention provides a non-naturally occurring Wood-Ljungdahl microorganism comprising (a) an enzyme that converts acetyl-CoA to acetoacetyl-CoA, (b) an enzyme that converts acetoacetyl-CoA to 3-hydroxybutyryl-CoA, and (c) an enzyme that converts 3-hydroxybutyryl-CoA to polyhydroxybutyrate, and methods related thereto.
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