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US Patent 11312749 Heterotandem bicyclic peptide complex

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Patent attributes

Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Gemma Mudd0

Kevin McDonnell0

Punit Upadhyaya0

Johanna Lahdenranta0

Date of Patent

April 26, 2022

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Patent Application Number

169415880

Date Filed

July 29, 2020

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Patent Citations

US Patent 10919937 Bicyclic peptide ligands and uses thereof

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US Patent 10875894 Multimeric bicyclic peptide ligands

Patent Citations Received

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US Patent 11696956 Bicyclic peptide ligands specific for EphA2

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US Patent 11746126 Bicyclic peptide ligands with detectable moieties and uses thereof

US Patent 11833211 Methods of suppression and treatment of disease comprising administering bicycle peptide ligands specific for EphA2

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US Patent 11912792 Bicyclic peptide ligands specific for nectin-4

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US Patent 11970553 Heterotandem bicyclic peptide complex

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US Patent 11623012 Bicyclic peptide ligands specific for EphA2

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Patent Primary Examiner

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The present invention relates to a heterotandem bicyclic peptide complex which comprises a first peptide ligand, which binds to EphA2, conjugated via a linker to two second peptide ligands, which bind to CD137. The invention also relates to the use of said heterotandem bicyclic peptide complex in preventing, suppressing or treating cancer.

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