A headset includes a housing defining an audio cavity, a speaker located within the audio cavity, and first and second sensor modules within the housing in spaced-apart, angled relationship to each other. The housing includes an aperture through which sound from the speaker can pass, and the first and second sensor modules are on opposing sides of a direction from the speaker to the aperture. The first sensor module is configured to direct electromagnetic radiation at a first target region of an ear of a person wearing the headset and to detect a first energy response signal therefrom that is associated with one or more physiological metrics of the subject, and the second sensor module is configured to direct electromagnetic radiation at a second target region of the ear and to detect a second energy response signal therefrom that is associated with the one or more physiological metrics.