Is a
Patent attributes
Patent Applicant
Patent Jurisdiction
Patent Number
Patent Inventor Names
Wen Shen0
Xue-hai Liang0
Eric E. Swayze0
Michael Oestergaard0
Michael T. Migawa0
Punit P. Seth0
Stanley T. Crooke0
Date of Patent
May 17, 2022
0Patent Application Number
169687010
Date Filed
February 12, 2019
0Patent Citations
Patent Citations Received
Patent Primary Examiner
The present disclosure provides oligomeric compound comprising a modified oligonucleotide having a central region comprising one or more modifications. In certain embodiments, the present disclosure provides oligomeric compounds having an improved therapeutic index or an increased maximum tolerated dose.
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