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US Patent 11364222 Combination therapy for treatment of cancer

Patent 11364222 was granted and assigned to G1 Therapeutics on June, 2022 by the United States Patent and Trademark Office.

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Patent attributes

Current Assignee

G1 Therapeutics

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Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Jiong Zhao0

Jay C. Strum0

Debra A. Tonetti0

Gregory R. Thatcher0

Rui Xiong0

Date of Patent

June 21, 2022

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Patent Application Number

164605020

Date Filed

July 2, 2019

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Patent Citations

US Patent 10703747 Benzothiophene-based selective mixed estrogen receptor downregulators

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US Patent 10807964 Benzothiophene-based selective estrogen receptor downregulators

US Patent 10829490 Substituted dihydropyrazino[1 ′,2′:1,5]pyrrolo[2,3-d]pyrimidine-based antiproliferative agents

US Patent 10925878 HSPC-sparing treatments for RB-positive abnormal cellular proliferation

US Patent 10966984 Transient protection of normal cells during chemotherapy

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Patent Citations Received

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US Patent 11643416 Substituted 1′,2′-dihydro-3′H-spiro[cyclohexane-1,4′-pyrimido[5′,4′:4,5]pyrrolo[2,1-c][1,2,4]triazin]-3′-ones as cyclin-dependent kinase inhibitors

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Patent Primary Examiner

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Compositions, combinations and methods comprising a CDK4/6 inhibitor of Formula D with a selective estrogen receptor downregulator of Formula A, B or C that are advantageous for the treatment of abnormal cellular proliferation, including a cancer or a tumor.

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