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US Patent 11376249 Organic compounds

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Is a

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Patent attributes

Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Kimberly Vanover0

Gretchen Snyder0

Sharon Mates0

Robert Davis0

Peng Li0

Wei Yao0

Date of Patent

July 5, 2022

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Patent Application Number

166340550

Date Filed

July 20, 2018

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Patent Citations

US Patent 10799500 Organic compounds

US Patent 10245260 Organic compounds

US Patent 10906906 Organic compounds

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US Patent 10961245 Substituted heterocycle fused gamma-carbolines for treatment of central nervous system disorders

Patent Citations Received

US Patent 12128043 Pharmaceutical capsules comprising lumateperone mono-tosylate

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US Patent 11773095 Organic compounds

US Patent 11958852 Compounds and methods

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US Patent 11980617 Methods of treating acute depression and/or acute anxiety

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US Patent 12023331 Methods

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US Patent 12090155 Methods

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US Patent 12122792 Pharmaceutical compositions comprising 4-((6bR,10aS)-3-methyl2,3,6b,9,10,10a-hexahydro-1H-pyrido[3′,4′:4,5]pyrrolo[1,2,3-de]quinoxalin8(7H)-yl)-1-(4-((6bR,10aS)-3-methyl-2,3,6b,9,10,10a-hexahydro-1H-pyrido[3′,4′:4,5]pyrrolo[1,2,3-de]quinoxalin-8(7H)-yl)phenyl)butan-1-one for treating conditions of the central nervous system and cardiac disorders

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US Patent 11753419 4-((6bR,10aS)-3-methyl-2,3,6b,9,10,10a-hexahydro-1H-pyrido[3′,4′:4,5]pyrrolo[1,2,3-de]quinoxalin-8(7H)-yl)-1-(4-((6bR,10aS)-3-methyl-2,3,6b,9,10,10a-hexahydro-1H-pyrido[3′4′:4,5]pyrrolo[1,2,3-de]quinoxalin-8(7H)-yl)phenyl)butan-1-one for treating conditions of the central nervous system and cardiac disorders

Patent Primary Examiner

Leslie A. Royds Draper

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The invention relates to particular substituted heterocycle fused gamma-carbolines, their prodrugs, in free, solid, pharmaceutically acceptable salt and/or substantially pure form as described herein, pharmaceutical compositions thereof, and methods of use in the treatment of diseases involving the 5-HT

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