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US Patent 11384375 Immobilized poly(n)polymerase

Patent 11384375 was granted and assigned to CureVac on July, 2022 by the United States Patent and Trademark Office.

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Patent Applicant

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Current Assignee

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Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Tilmann Roos0

Markus Conzelmann0

Veronika Wagner0

Benyamin Yazdan Panah0

Date of Patent

July 12, 2022

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Patent Application Number

155701950

Date Filed

May 2, 2016

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Patent Citations Received

US Patent 12083190 Rabies vaccine

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US Patent 11786590 Rotavirus vaccines

US Patent 11834651 Method for producing and purifying RNA, comprising at least one step of tangential flow filtration

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US Patent 11965000 Respiratory syncytial virus (RSV) vaccine

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Patent Primary Examiner

Richard G Hutson

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The present invention relates to an immobilized poly(N)polymerase (PNP), methods of producing said PNP and uses thereof. Further disclosed is an enzyme reactor and kit comprising the PNP for producing polynucleotidylated ribonucleic acid poly(N)RNA)molecules which are useful in gene therapy, immunotherapy, protein replacement therapy and/or vaccination.

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