A biopsy device includes a body, a needle, a tissue sample holder and a sensor. The needle extends from the body. The tissue sample holder is in communication with the needle to receive one or more tissue samples within a sample chamber defined by the tissue sample holder. The tissue sample holder includes a receiving cavity. The sensor is configured to detect x-rays. The receiving cavity is sized and shaped to receive the sensor such that the sensor is removably positioned within the tissue sample holder.