Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Jasper Z. Williams0
Wendell A. Lim0
Kole T. Roybal0
Date of Patent
August 2, 2022
Patent Application Number
16325657
Date Filed
August 22, 2017
Patent Citations
Patent Primary Examiner
The instant disclosure provides chimeric polypeptides which modulate various cellular processes following a cleavage event induced upon binding of a specific binding member of the polypeptide with its binding partner. Methods of using chimeric polypeptides to modulate cellular functions, including e.g., induction of gene expression, are also provided. Nucleic acids encoding the subject chimeric polypeptides and associated expression cassettes and vectors as well as cells that contain such nucleic acids and/or expression cassettes and vectors are provided. Also provided, are methods of treating a subject using the described components and methods as well as kits for practicing the subject methods.
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