Is a
Patent attributes
Patent Applicant
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Ivan Krivega0
Jeffrey C. Miller0
Lei Zhang0
Russell DeKelver0
Date of Patent
August 2, 2022
0Patent Application Number
162712500
Date Filed
February 8, 2019
0Patent Citations
Patent Primary Examiner
CPC Code
Described herein are engineered nucleases comprising mutations in the cleavage domain (e.g., FokI or homologue thereof) and/or DNA binding domain (zinc finger protein, TALE, single guide RNA) such that on-target specificity is increased.
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