The present disclosure provides a driving circuit and a liquid crystal display device. The driving circuit is configured to drive the liquid crystal to display and includes liquid crystal driving chips configured to receive original Gamma voltage; a time sequence control chip configured to receive the original Gamma voltages transmitted by the liquid crystal driving chips and output Gamma voltage adjust correcting parameters to the liquid crystal driving chips; the liquid crystal driving chip compensating and correcting the original Gamma voltage according to the Gamma voltage adjust correcting parameters to make Gamma voltages of each of the liquid crystal driving chips equal.