US Patent 11419619 Method and system for treating lesions

A method of and a system for treating a lesion. A waveguide is inserted into a vessel of a subject, with the lesion being present in the vessel and the waveguide extending longitudinally between a proximal end and a distal end. The distal end of the waveguide is positioned adjacent to the lesion, and a high amplitude broadband mechanical pulse is generated and propagated from the proximal end to the distal end of the waveguide. At least a portion of the high amplitude broadband mechanical pulse is propagated from the distal end of the waveguide to the lesion, with the at least a portion of the high amplitude broadband mechanical pulse propagating up to the lesion, thereby treating at least partially the lesion.