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US Patent 11419851 Oral formulations of pyrrolidine derivatives

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Contents

Is a
Patent
Patent

Patent attributes

Patent Applicant
ObsEva
ObsEva
Current Assignee
ObsEva
ObsEva
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
11419851
Date of Patent
August 23, 2022
Patent Application Number
16569065
Date Filed
September 12, 2019
Patent Citations
‌
US Patent 10047048 Pyrrolidine derivatives as oxytocin/vasopressin V1a receptors antagonists
‌
US Patent 10478420 Oral formulations of pyrrolidine derivatives
‌
US Patent 10604482 Pyrrolidine derivatives as oxytocin/vasopressin via receptors antagonists
Patent Primary Examiner
‌
Theodore R. Howell
CPC Code
‌
A61K 9/2018
‌
A61K 9/2054
‌
A61K 9/0056
‌
A61K 9/0095
‌
A61K 47/40
‌
A61K 9/20
‌
A61K 9/2009
‌
A61K 9/2013
...

The present invention relates to solid oral formulations comprising a compound of formula (3Z,5S)-5-(hydroxymethyl)-1-[(2′-methyl-1,1′-biphenyl-4-yl)carbonyl]pyrrolidin-3-one O-methyloxime, and/or an active metabolite thereof, and the use of said formulations in the treatment and/or prevention of preterm labor, premature birth, dysmenorrhea and embryo implantation failure due to uterine contractions. The present invention is furthermore related to processes for their preparation.

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