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US Patent 11492590 Protein modification of living cells using sortase

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Patent attributes

Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Lee Kim Swee0

Hidde L. Ploegh0

Date of Patent

November 8, 2022

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Patent Application Number

163816540

Date Filed

April 11, 2019

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Patent Citations

US Patent 10260038 Protein modification of living cells using sortase

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US Patent 10335504 Heterocyclic molecules for biomedical imaging and therapeutic applications

US Patent 10556024 None

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US Patent 10471099 In vitro production of red blood cells with proteins comprising sortase recognition motifs

US Patent 11028185 Using sortases to install click chemistry handles for protein ligation

US Patent 10053683 Intercellular labeling of ligand-receptor interactions

US Patent 10081684 Using sortases to install click chemistry handles for protein ligation

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Patent Citations Received

US Patent 11992505 In vitro production of red blood cells with proteins comprising sortase recognition motifs

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US Patent 12059413 Methods of inhibiting viruses using compositions targeting TSG101-ubiquitin interaction

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US Patent 11850216 18F labeling of proteins using sortases

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Patent Primary Examiner

Robert J Yamasaki

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CPC Code

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Non-genetically engineered mammalian cells modified by sortase-mediated conjugation of an agent thereto are provided. Methods of conjugating agents to non-genetically engineered mammalian cells using sortase are provided. Methods of using the cells, e.g., for diagnostic and/or therapeutic purposes, are provided.

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