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US Patent 11510990 Conjugates of fusion proteins of GLP-1 and FGF21

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Patent attributes

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

Date of Patent

November 29, 2022

Patent Application Number

17485424

Date Filed

September 26, 2021

Patent Citations

US Patent 10138291 Factor VIII complex with XTEN and von Willebrand Factor protein, and uses thereof

US Patent 10172953 XTEN conjugate compositions and methods of making same

US Patent 10407479 Mutant FGF-21 peptide pegylated conjugates and uses thereof

US Patent 10413590 Methods of using compositions comprising variants of FGF19 polypeptides for reducing body mass in a subject

US Patent 10421798 Factor VIII compositions and methods of making and using same

US Patent 10583174 FGF21 compound / GLP-1R agonist combinations with optimized activity ratio

US Patent 10548953 Factor VIII-XTEN fusions and uses thereof

US Patent 10669323 Methods of treating metabolic disorders with dual function fibroblast growth factor 21 proteins

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Patent Primary Examiner

The present disclosure provides conjugates of polypeptides comprising GLP-1, polypeptide linker and FGF21. Pharmaceutical compositions comprising the same and methods of treating diseases are also provided.

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