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US Patent 11512314 Amphiphilic polynucleotides

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Patent Applicant

Duke University

Current Assignee

Duke University

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

Date of Patent

November 29, 2022

Patent Application Number

16927982

Date Filed

July 13, 2020

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Patent Primary Examiner

Compositions and methods disclosed herein can help provide improved delivery of non-natural therapeutic nucleotides for the treatment of diseases such as cancer. An example composition includes an assembly of amphiphilic polynucleotides, where each amphiphilic polynucleotide includes an aptamer portion, a first nucleotide portion, and a second nucleotide portion.

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