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US Patent 11519022 Spatially encoded biological assays

Patent 11519022 was granted and assigned to PROGNOSYS BIOSCIENCES, INC. on December, 2022 by the United States Patent and Trademark Office.

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Patent attributes

Patent Applicant

PROGNOSYS BIOSCIENCES, INC.

Current Assignee

PROGNOSYS BIOSCIENCES, INC.

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

Date of Patent

December 6, 2022

Patent Application Number

17850538

Date Filed

June 27, 2022

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Patent Citations Received

US Patent 12129516 Quantitative and automated permeabilization performance evaluation for spatial transcriptomics

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US Patent 11753675 Generating capture probes for spatial analysis

US Patent 11768175 Electrophoretic methods for spatial analysis

US Patent 11773433 Methods for spatial analysis using targeted RNA depletion

US Patent 11788122 Methods of detecting analytes

US Patent 11835462 Methods and compositions for partitioning a biological sample

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US Patent 11859178 Nucleic acid library methods

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US Patent 11866767 Simultaneous spatio-temporal measurement of gene expression and cellular activity

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Patent Primary Examiner

CPC Code

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The present invention provides assays and assay systems for use in spatially encoded biological assays. The invention provides an assay system comprising an assay capable of high levels of multiplexing where reagents are provided to a biological sample in defined spatial patterns; instrumentation capable of controlled delivery of reagents according to the spatial patterns; and a decoding scheme providing a readout that is digital in nature.

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