A system and method of masonry construction using masonry blocks and anchors, wherein the blocks are laid end to end, and an anchor is inserted between them. The anchor both spaces and secures the blocks, even before mortar is applied. The anchors contain legs recess between the walls of the masonry construction, and create a space for the walls to recess in to on the anchor, thereby providing multi-directional securement of the system. Embodiments of the system also contain grooves for additional securement and complemental engagement of the anchors.