A control system and pathogen inactivation method to reduce cross-contamination within operational devices that experience sequential touching of touch spots on the operational device by multiple people. Additionally, the system controls and then executes the reconfiguration of touch spot position to increase the probabilistic time interval between sequential touches from a first person to a second person physically interacting with the operational device. The dynamic reconfiguration control system reduces the probability of cross-contamination between sequential personal touches in sequential user sessions.