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Patent Applicant
Current Assignee
Patent Jurisdiction
Patent Number
Date of Patent
December 20, 2022
Patent Application Number
16770923
Date Filed
December 10, 2018
Patent Citations
Patent Primary Examiner
Recombinant DPO4-type DNA polymerase variants with amino acid substitutions that confer modified properties upon the polymerase for improved single molecule sequencing applications are provided. Such properties may include enhanced binding and accurate incorporation of bulky nucleotide analog substrates into daughter strands and the like. Also provided are compositions comprising such DPO4 variants and nucleotide analogs, as well as nucleic acids which encode the polymerases with the aforementioned phenotypes.
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