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US Patent 11535833 Carboxyesterase biocatalysts

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Contents

Is a
Patent
Patent

Patent attributes

Patent Applicant
GlaxoSmithKline
GlaxoSmithKline
Current Assignee
GlaxoSmithKline
GlaxoSmithKline
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
11535833
Date of Patent
December 27, 2022
Patent Application Number
16771279
Date Filed
December 13, 2018
Patent Primary Examiner
‌
Tekchand Saidha
CPC Code
‌
C12N 9/16
‌
C12N 15/113
‌
C12N 9/18
‌
C12Y 301/00
‌
C12P 19/14
‌
C12N 15/8213
‌
C12N 9/54

The present disclosure provides engineered carboxyesterase enzymes that have the ability to catalyze amide bond formation. Also provided are polynucleotides encoding the carboxyesterase enzymes, host cells capable of expressing the engineered carboxyesterase enzymes, and methods of using the engineered carboxyesterase enzymes to make commercially valuable amides. Also provided are amides that are made using the engineered carboxyesterase enzymes.

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