A fingerprint sensing device and an operation method thereof are provided. The fingerprint sensing device includes a driver integrated chip and a fingerprint sensor. The driver integrated chip is coupled to a host processor. The fingerprint sensor is coupled to the driver integrated chip and the host processor. The fingerprint sensor obtains a fingerprint image during a period when the host processor is in the sleep mode. The driver integrated chip performs a fingerprint verification on the fingerprint image, and the driver integrated chip determines to wake up the host processor according to whether the fingerprint image passes the fingerprint verification.