Is a
Patent attributes
Patent Applicant
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Michael J. Massare0
Gale Smith0
Jing-Hui Tian0
Date of Patent
January 3, 2023
0Patent Application Number
171703670
Date Filed
February 8, 2021
0Patent Citations
Patent Primary Examiner
Disclosed herein are coronavirus Spike (S) proteins and nanoparticles comprising the same, which are suitable for use in vaccines. The nanoparticles present antigens from pathogens surrounded to and associated with a detergent core resulting in enhanced stability and good immunogenicity. Dosages, formulations, and methods for preparing the vaccines and nanoparticles are also disclosed.
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