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US Patent 11548948 FC binding fragments comprising a PD-L1 antigen-binding site

Patent 11548948 was granted and assigned to F-star on January, 2023 by the United States Patent and Trademark Office.

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The application relates to specific binding members which bind to programmed death-ligand (PD-L1). The specific binding members preferably comprise a PD-L1 antigen-binding site located in structural loops of a constant domain of the specific binding member. The specific binding members find application, for example, in the treatment of cancer, as well as infectious diseases, inflammation, diseases and conditions associated with inflammation, and inflammatory diseases.

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