Is a
Patent attributes
Patent Applicant
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Rui D. Pinto0
Robert A. Kramer0
Mark Throsby0
Erwin Houtzager0
Cornelis A. De Kruif0
Ton Logtenberg0
Date of Patent
January 24, 2023
0Patent Application Number
158706210
Date Filed
January 12, 2018
0Patent Citations
Patent Citations Received
Patent Primary Examiner
Described are transgenic, non-human animals comprising a nucleic acid encoding an immunoglobulin light chain, whereby the immunoglobulin light chain is human, human-like, or humanized. The nucleic acid is provided with a means that renders it resistant to DNA rearrangements and/or somatic hypermutations. In one embodiment, the nucleic acid comprises an expression cassette for the expression of a desired molecule in cells during a certain stage of development in cells developing into mature B cells. Further provided is methods for producing an immunoglobulin from the transgenic, non-human animal.
Timeline
No Timeline data yet.
Further Resources
No Further Resources data yet.