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US Patent 11560437 Stable multispecific antibodies

Patent 11560437 was granted and assigned to Biomunex Pharmaceuticals on January, 2023 by the United States Patent and Trademark Office.

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Patent attributes

Patent Applicant

Biomunex Pharmaceuticals

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Current Assignee

Biomunex Pharmaceuticals

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Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Eugene Zhukovsky0

Richard J. Morse0

Olivier Leger0

Date of Patent

January 24, 2023

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Patent Application Number

164984210

Date Filed

March 27, 2018

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Patent Citations

US Patent 10815310 Multispecific antigen binding fragments and multispecific antibodies derived therefrom comprising mutant CH1 and CL-kappa domains

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US Patent 10487156 Asymmetric multispecific antibodies

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US Patent 10633456 Vista antigen-binding molecules

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US Patent 10662241 HER3 antigen-binding molecules

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US Patent 11046776 Multivalent and multiepitopic antibodies having agonistic activity and methods of use

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Patent Citations Received

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Patent Primary Examiner

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CPC Code

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The invention relates to multispecific antibody constructs comprising Fab fragments having a particular set of mutations at the interface of the CH1 and CL domains, the mutations preventing heavy chain/light chain mispairing.

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