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US Patent 11566005 Highly pure phentolamine mesylate and methods for making same

Patent 11566005 was granted and assigned to Ocuphire Pharma, Inc. on January, 2023 by the United States Patent and Trademark Office.

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Patent attributes

Patent Applicant

Ocuphire Pharma, Inc.

Current Assignee

Ocuphire Pharma, Inc.

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

Date of Patent

January 31, 2023

Patent Application Number

17747656

Date Filed

May 18, 2022

Patent Citations

US Patent 10772829 Aqueous ophthalmic solutions of phentolamine and medical uses thereof

US Patent 10993932 Methods and compositions for treatment of presbyopia, mydriasis, and other ocular disorders

US Patent 11000509 Methods and compositions for daily ophthalmic administration of phentolamine to improve visual performance

US Patent 11400077 Methods and compositions for treatment of presbyopia, mydriasis, and other ocular disorders

US Patent 11090261 Aqueous ophthalmic solutions of phentolamine and medical uses thereof

US Patent 10064818 Compositions and methods for the treatment of presbyopia

US Patent 10278918 Aqueous ophthalmic solutions of phentolamine and medical uses thereof

US Patent 10507245 Ophthalmic formulation and method for ameliorating presbyopia

...

Patent Citations Received

US Patent 11976044 Highly pure phentolamine mesylate

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Patent Primary Examiner

CPC Code

This invention provides methods for synthesizing phentolamine mesylate from phentolamine and methanesulfonic acid in the presence of acetone and water. The methods of the present invention provide highly pure phentolamine mesylate. The invention also provides highly pure phentolamine mesylate.

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