Is a
Patent attributes
Patent Jurisdiction
Patent Number
Date of Patent
February 21, 2023
Patent Application Number
16348335
Date Filed
November 8, 2017
Patent Citations
Patent Citations Received
Patent Primary Examiner
The disclosure features a lipid nanoparticle (LNP) formulation comprising a plurality of LNPs and a stabilizing agent that mitigates the degradation of the LNPs or a subpopulation thereof. Lipid nanoparticles further including therapeutics and/or prophylactics such as RNA are useful in the delivery of therapeutics and/or prophylactics to mammalian cells or organs to, for example, regulate polypeptide, protein, or gene expression. Methods of manufacturing LNP formulations and screening for a stabilizing agent are also disclosed.
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