Is a
Patent attributes
Patent Jurisdiction
Patent Number
Date of Patent
February 21, 2023
Patent Application Number
17752978
Date Filed
May 25, 2022
Patent Citations
...
Patent Primary Examiner
CPC Code
The problem to be solved is to provide a humanized anti-IL-6 receptor antibody MRA-containing formulation which is suitable for subcutaneous administration, wherein dimerization or deamidation is prevented during long-term storage. The present application is directed to a stable antibody-containing liquid formulation characterized by containing arginine and histidine buffer. A method of inhibiting deamidation or dimerization of such an antibody in a concentrated liquid formulation includes histidine buffer in the liquid formulation.
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