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US Patent 11603531 Methods and compositions for modulating splicing

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Patent Citations

US Patent 10076519 Substituted pyridazines as skeletal muscle modulators

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Patent Citations

US Patent 10053697 Programmable alternative splicing devices and uses thereof

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Patent Citations

US Patent 10006027 Methods for modulating Ataxin 2 expression

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US Patent 10252984 Inhibiting G protein coupled receptor 6 kinase polypeptides

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US Patent 10358427 Modulators of indoleamine 2,3-dioxygenase

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US Patent 10195196 1,4-disubstituted pyridazine analogs there of and methods for treating SMN-deficiency-related conditions

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US Patent 10093678 Azaspiro derivatives as TRPM8 antagonists

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US Patent 11603531 Methods and compositions for modulating splicing

Article

Described herein are small molecule splicing modulator compounds that modulate splicing of mRNA, such as pre-mRNA, encoded by genes, and methods of use of the small molecule splicing modulator compounds for modulating splicing and treating diseases and conditions.

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Is a

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Patent Applicant

Skyhawk Therapeutics

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Current Assignee

Skyhawk Therapeutics

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Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

116035310

Date of Patent

March 14, 2023

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Patent Application Number

175028240

Date Filed

October 15, 2021

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Patent Citations

US Patent 10006027 Methods for modulating Ataxin 2 expression

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US Patent 10053697 Programmable alternative splicing devices and uses thereof

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US Patent 10076519 Substituted pyridazines as skeletal muscle modulators

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US Patent 10093678 Azaspiro derivatives as TRPM8 antagonists

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US Patent 10112923 1,2,4-triazine-4-amine derivatives

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US Patent 10195196 1,4-disubstituted pyridazine analogs there of and methods for treating SMN-deficiency-related conditions

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US Patent 10196639 Modulation of gene expression and screening for deregulated protein expression

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US Patent 10252984 Inhibiting G protein coupled receptor 6 kinase polypeptides

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US Patent 10358427 Modulators of indoleamine 2,3-dioxygenase

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US Patent 10377742 AMPK-activating heterocyclic compounds and methods for using the same

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Patent Primary Examiner

Kristin A Vajda

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CPC Code

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