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US Patent 11629189 Bispecific antibody for ICOS and PD-L1

Patent 11629189 was granted and assigned to Kymab on April, 2023 by the United States Patent and Trademark Office.

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Is a
Patent
Patent
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Patent attributes

Patent Applicant
Kymab
Kymab
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Current Assignee
Kymab
Kymab
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
116291890
Patent Inventor Names
Fadi Badr0
Richard Charles Alfred Sainson0
Ryan Fiehler0
Stephen John Arkinstall0
Francisca Wollerton Van Horck0
Frederick Akele0
Jamie Iain Campbell0
Matthew John McCourt0
...
Date of Patent
April 18, 2023
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Patent Application Number
169552190
Date Filed
December 19, 2018
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Patent Citations
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US Patent 10266608 Fabs-in-tandem immunoglobulin and uses thereof
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US Patent 10517949 Anti-PD-L1 antibodies
Patent Citations Received
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US Patent 11858996 Anti-ICOS antibodies
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Patent Primary Examiner
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Ilia I Ouspenski
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Multispecific antibody in mAb2 format, comprising an ICOS-binding Fab region and a PD-L1-binding Fcab region. Use of the multispecific antibody in immuno-oncology, including for treatment of solid tumours. Combination therapy including antibody to another immune checkpoint molecule such as PD-1 and CTLA-4, in addition to anti-ICOS and anti-PD-L1.

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