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US Patent 11634460 Non-neuronal snare-cleaving botulinum neurotoxins

Patent 11634460 was granted and assigned to Ipsen on April, 2023 by the United States Patent and Trademark Office.

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Patent
Patent
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Patent attributes

Patent Applicant
Ipsen
Ipsen
0
Current Assignee
Ipsen
Ipsen
0
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
0
Patent Number
116344600
Patent Inventor Names
Thomas Binz0
Stefan Sikorra0
Date of Patent
April 25, 2023
0
Patent Application Number
167548440
Date Filed
January 29, 2019
0
Patent Primary Examiner
‌
S. Devi
0

The present invention provides a modified botulinum neurotoxin A (BoNT/A) L-chain protease that demonstrates enhanced cleaveage of human SNAP-23 (hSNAP-23) relative to unmodified (wild-type) BoNT/A L-chain protease, together with the use thereof for cleaving hSNAP-23.

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