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US Patent 11638760 Pyrrolobenzodiazepine antibody conjugates

Patent 11638760 was granted and assigned to Mersana Therapeutics on May, 2023 by the United States Patent and Trademark Office.

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Patent attributes

Patent Applicant

Mersana Therapeutics

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Current Assignee

Mersana Therapeutics

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Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Timothy B. Lowinger0

Joshua D. Thomas0

Mao Yin0

Shuyi Tang0

Aleksandr V. Yurkovetskiy0

Brian D. Jones0

Date of Patent

May 2, 2023

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Patent Application Number

167669140

Date Filed

November 27, 2018

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Patent Citations

US Patent 10947317 NaPi2b-targeted antibody-drug conjugates and methods of use thereof

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US Patent 10143695 Pyrrolobenzodiazepines and conjugates thereof

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US Patent 10526294 Pyrrolobenzodiazepines and conjugates thereof

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US Patent 10660901 Pyrrolobenzodiazepines and conjugates thereof

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US Patent 11135307 Peptide-containing linkers for antibody-drug conjugates

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Patent Primary Examiner

Samantha L Shterengarts

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The present disclosure relates generally to antibody-drug conjugates comprising pyrrolo[2, 1-c][1, 4]benzodiazepine (PBD) drug moieties. The present disclosure also relates to methods of using these conjugates, e.g., as therapeutics and/or diagnostics.

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