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US Patent 11685750 Crystalline forms of IRAK degraders

Patent 11685750 was granted and assigned to Kymera Therapeutics on June, 2023 by the United States Patent and Trademark Office.

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Patent Citations Received
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US Patent 12091411 IRAK degraders and uses thereof
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Edits on 28 Jun, 2023
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 US Patent 11685750 Crystalline forms of IRAK degraders

Article

The present disclosure relates generally to various forms, salts and compositions of compounds useful for the modulation of one or more interleukin-1 receptor-associated kinases (“IRAK”) via ubiquitination and/or degradation and uses of the same in the treatment various diseases.

Infobox
Is a
Patent
Patent
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Patent Applicant
Kymera Therapeutics
Kymera Therapeutics
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Current Assignee
Kymera Therapeutics
Kymera Therapeutics
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
116857500
Date of Patent
June 27, 2023
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Patent Application Number
173384200
Date Filed
June 3, 2021
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Patent Citations
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US Patent 7173015 Inhibition of Syk kinase expression
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US Patent 7208157 Proteolysis targeting chimeric pharmaceutical
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US Patent 7273920 Controlling protein levels in eucaryotic organisms
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US Patent 7390799 Apoptosis promoters
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US Patent 7402325 Supercritical carbon dioxide extract of pharmacologically active components from
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US Patent 7449458 Prodrugs of 2,4-pyrimidinediamine compounds and their uses
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US Patent 7501496 Anti-OX40L antibodies
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US Patent 7528143 Bi-aryl meta-pyrimidine inhibitors of kinases
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US Patent 7557210 2,4-pyrimidinediamine compounds and their uses
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US Patent 7598257 Heteroaryl substituted pyrrolo[2,3-b]pyridines and pyrrolo[2,3-b]pyrimidines as janus kinase inhibitors
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US Patent 7622496 Modified lysine-mimetic compounds
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US Patent 7667039 1,3-dihydro-imidazo [4,5-C] quinolin-2-ones as lipid kinase inhibitors
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US Patent 7713943 Further use of protein kinase N beta
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US Patent 7989622 Phosphatidylinositol 3-kinase inhibitors and methods of their use
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US Patent 8138347 Quinoline derivatives as PI3 kinase inhibitors
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US Patent 8185616 Route designing method
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US Patent 8217035 Pyrimidine derivatives used as PI-3-kinase inhibitors
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US Patent 8338439 2,4-disubstituted pyrimidines useful as kinase inhibitors
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US Patent 8486941 Phenyl amino pyrimidine compounds and uses thereof
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US Patent 8906682 Methods for treatment of cancer
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US Patent 9500653 Small-molecule hydrophobic tagging of fusion proteins and induced degradation of same
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US Patent 9694084 Methods to induce targeted protein degradation through bifunctional molecules
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US Patent 9750816 Methods to induce targeted protein degradation through bifunctional molecules
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US Patent 9770512 Methods to induce targeted protein degradation through bifunctional molecules
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US Patent 9821068 Methods to induce targeted protein degradation through bifunctional molecules
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US Patent 9969710 Heteroaryl compounds as IRAK inhibitors and uses thereof
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US Patent 10125114 Methods to induce targeted protein degradation through bifunctional molecules
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US Patent 10336744 1AP E3 ligase directed proteolysis targeting chimeric molecules
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US Patent 10874743 IRAK degraders and uses thereof
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US Patent 11352350 IRAK degraders and uses thereof
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Patent Primary Examiner
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John M Mauro
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CPC Code
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C07B 2200/13
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C07D 519/00
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A61P 29/00
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