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US Patent 11685790 Antibodies binding to STEAP-1

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Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Date of Patent

June 27, 2023

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Patent Application Number

173999880

Date Filed

August 11, 2021

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Patent Citations

US Patent 7166714 Serpentine transmembrane antigens expressed in human cancers and uses thereof

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US Patent 7189826 Monoclonal human natural antibodies

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US Patent 7332581 Polypeptide variants with altered effector function

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US Patent 7494646 Antibodies and molecules derived therefrom that bind to STEAP-1 proteins

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US Patent 7521541 Cysteine engineered antibodies and conjugates

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US Patent 7527791 Humanized anti-TGF-beta antibodies

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US Patent 7575749 Serpentine transmembrane antigens expressed in human cancers and uses thereof

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US Patent 7642054 Serpentine transmembrane antigens expressed in human cancers and uses thereof

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Patent Primary Examiner

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The present invention generally relates to antibodies that bind to STEAP-1, including bispecific antigen binding molecules e.g. for activating T cells. In addition, the present invention relates to polynucleotides encoding such antibodies, and vectors and host cells comprising such polynucleotides. The invention further relates to methods for producing the antibodies, and to methods of using them in the treatment of disease.

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