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US Patent 11685958 Methylation markers and targeted methylation probe panel

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Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Date of Patent

June 27, 2023

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Patent Application Number

172141050

Date Filed

March 26, 2021

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Patent Citations

US Patent 9868756 Method for bisulfite treatment

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US Patent 10704083 Modification of DNA on magnetic beads

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US Patent 10718026 Methylation assay

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US Patent 11410750 Methylation markers and targeted methylation probe panel

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US Patent 7371526 Method and materials for bisulfite conversion of cytosine to uracil

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US Patent 7413855 Method for bisulfite treatment

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US Patent 7655399 Methods for prenatal diagnosis of chromosomal abnormalities

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US Patent 7700282 Method for the carry-over protection in DNA amplification systems targeting methylation analysis achieved by a modified pre-treatment of nucleic acids

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Patent Primary Examiner

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The present description provides a cancer assay panel for targeted detection of cancer-specific methylation patterns. Further provided herein are methods of designing, making, and using the cancer assay panel for the diagnosis of cancer.

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