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US Patent 11701351 Treatment of gliomas using organonitro compound combination therapy

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Patent Applicant

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Current Assignee

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Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Date of Patent

July 18, 2023

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Patent Application Number

172234220

Date Filed

April 6, 2021

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Patent Citations

US Patent 8664247 Acyclic organonitro compounds for use in treating cancer

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US Patent 8927527 Cyclic nitro compounds, pharmaceutical compositions thereof and uses thereof

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US Patent 9226915 Cyclic nitro compounds, pharmaceutical compositions thereof and uses thereof

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US Patent 9468625 Organonitro thioether compounds and medical uses thereof

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US Patent 9987270 Treatment of gliomas using organonitro compound combination therapy

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US Patent 10149832 Cyclic nitro compounds, pharmaceutical compositions thereof and uses thereof

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US Patent 10342778 Treatment of brain metastases using organonitro compound combination therapy

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Patent Primary Examiner

Kristin A Vajda

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CPC Code

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The invention provides therapeutic methods and kits for treating a glioma using a particular dosing regimen of the organonitro compound ABDNAZ, radiation therapy, and one of temozolomide, irinotecan, or bevacizumab.

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