US Patent 11708274 Synthesis of polyethylenimine-silica janus nanoparticles

Embodiments of the disclosure provide an asymmetrically functionalized nanoparticle and a method for synthesizing the same. The asymmetrically functionalized nanoparticle includes a base nanoparticle. The base nanoparticle can include silicon dioxide. The base nanoparticle can have a lipophilic surface. A portion of the surface can be functionalized with a functionalizing material forming a hydrophilic portion. The functionalizing material can include polyethylenimine. A remaining portion of the surface is not functionalized forming a lipophilic portion. The asymmetrically functionalized nanoparticle is amphiphilic.