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Patent Applicant
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Patent Number
Date of Patent
July 25, 2023
0Patent Application Number
166104600
Date Filed
May 3, 2018
0Patent Citations
Patent Primary Examiner
CPC Code
Recombinant DP04-type DNA polymerase variants with amino acid substitutions that confer modified properties upon the polymerase for improved single molecule sequencing applications are provided. Such properties may include enhanced binding and incorporation of bulky nucleotide analog substrates into daughter strands and the like. Also provided are compositions comprising such DP04 variants and nucleotide analogs, as well as nucleic acids which encode the polymerases with the aforementioned phenotypes.
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