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US Patent 11747351 Assays to monitor bleeding disorders

Patent 11747351 was granted and assigned to Bioverativ on September, 2023 by the United States Patent and Trademark Office.

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Patent attributes

Patent Applicant

Current Assignee

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

Patent Inventor Names

Xin Zhang

Buyue Yang

Jurg Sommer

Glenn Pierce

Haiyan Jiang

Date of Patent

September 5, 2023

Patent Application Number

16848445

Date Filed

April 14, 2020

Patent Citations

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US Patent 8449884 Clotting factor-fc chimeric proteins to treat hemophilia

US Patent 8455439 Antidotes for factor Xa inhibitors and methods of using the same in combination with blood coagulating agents

US Patent 10656167 Assays to monitor bleeding disorders

US Patent 8815250 Clotting factor-Fc chimeric proteins to treat hemophilia

US Patent 7348004 Immunoglobulin chimeric monomer-dimer hybrids

US Patent 7381408 Methods for chemically synthesizing immunoglobulin chimeric proteins

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Patent Primary Examiner

Michael Szperka

The present invention provides methods of dosing Factor VIII or Factor IX chimeric and hybrid polypeptides. The present invention further provides high-sensitivity methods of quantifying an amount of activated FIX protein in a test sample.

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