A collapsible travel case includes a plurality of panels that are each non-removably secured to at least one other panel of the plurality of panels. Each panel of a subset of the panels may be removably secured to another panel of the subset of panels such that the plurality of panels define a substantially cuboid shape. A top panel may define a top opening with a closure mechanism. A bottom panel may be foldable and insertable within the top opening with other panels of the plurality of panels folded between the top panel and the bottom panel. The bottom panel may include a retractable stiffening element. Panels may define openings through which flaps secured to other panels may insert and be secured within using fastening material.