US Patent 11753640 Oligonucleotides for modulating Tau expression
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US Patent 11753640 Oligonucleotides for modulating Tau expression
Article
The present invention relates to antisense oligonucleotides that are capable of modulating expression of Tau in a target cell. The oligonucleotides hybridize to MAPT mRNA. The present invention further relates to conjugates of the oligonucleotide and pharmaceutical compositions and methods for treatment of Tauopathies, Alzheimzer's disease, fronto-temporal dementia (FTD), FTDP-17, progressive supranuclear palsy (PSP), chronic traumatic encephalopathy (CTE), corticobasal ganglionic degeneration (CBD), epilepsy, Dravet syndrome, depression, seizure disorders and movement disorders.
Infobox
Is a
Patent Jurisdiction
Patent Number
11753640
Patent Inventor Names
Anja Mølhart Høg
Marianne L. Jensen
Peter Hagedorn
Richard E. Olson
Date of Patent
September 12, 2023
Patent Application Number
17139161
Date Filed
December 31, 2020
Patent Citations
Patent Primary Examiner
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