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US Patent 11761009 Artificial nucleic acid molecules for improved protein expression

Patent 11761009 was granted and assigned to CureVac on September, 2023 by the United States Patent and Trademark Office.

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Is a

Patent attributes

Patent Applicant

Current Assignee

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

Patent Inventor Names

Andreas Thess

Thomas Schlake

Stefanie Grund

Date of Patent

September 19, 2023

Patent Application Number

17713533

Date Filed

April 5, 2022

Patent Citations

US Patent 9155788 Application of mRNA for use as a therapeutic against tumour diseases

US Patent 9226959 Nucleic acids comprising formula (N

US Patent 9234013 Nucleic acid comprising or coding for a histone stem-loop and a poly(A) sequence or a polyadenylation signal for increasing the expression of an encoded protein

US Patent 9314535 Disulfide-linked polyethyleneglycol/peptide conjugates for the transfection of nucleic acids

US Patent 9352028 Composition for treating lung cancer, particularly of non-small lung cancers (NSCLC)

US Patent 9402887 Composition for treating prostate cancer (PCa)

US Patent 9421255 Vaccine composition comprising complexed immunostimulatory nucleic acids and antigens packaged with disulfide-linked polyethyleneglycol/peptide conjugates

US Patent 9433669 Application of mRNA for use as a therapeutic against tumor diseases

...

Patent Citations Received

US Patent 11965000 Respiratory syncytial virus (RSV) vaccine

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Patent Primary Examiner

Samuel C Woolwine

Patent abstract

The invention relates to an artificial nucleic acid molecule or a vector comprising an open reading frame and a 3′-UTR comprising at least two poly(A) sequences. The invention also relates to a method for increasing protein production from an artificial nucleic acid molecule and to the use of a

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