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US Patent 11767346 Modified AAV capsid proteins and uses thereof

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Is a

Patent attributes

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

Patent Inventor Names

Damien Marsic

Sanford L. Boye

Shannon E. Boye

Sergei Zolotukhin

Paul D. Gamlin

Date of Patent

September 26, 2023

Patent Application Number

17689324

Date Filed

March 8, 2022

Patent Citations

US Patent 9157098 Transduction efficiency, capsid-modified rAAV vectors and methods of use

US Patent 7186552 Adeno-associated virus serotype 1 nucleic acid sequences, vectors and host cells containing same

US Patent 7220577 Modified AAV

US Patent 7927585 Production of recombinant AAV virions

US Patent 8445267 Tyrosine-modified recombinant rAAV vector compositions and methods for use

US Patent 9677088 Adeno associated virus plasmids and vectors

US Patent 9725485 AAV vectors with high transduction efficiency and uses thereof for gene therapy

US Patent 10011640 Capsid-modified rAAV vector compositions and methods therefor

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Patent Primary Examiner

CPC Code

C12N 2750/14145

C12N 2750/14011

C12N 2750/14143

...

Patent abstract

Adeno associated viral (AAV) particles are emerging as a useful vehicle for gene delivery to various organs and tissues, one of them being the retina. Provided here are variant AAV (for example, variant serotype 2 (AAV2)) capsid proteins and variant capsid protein containing particles with enhanced ability to transduce retinal cells.

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